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However, in lung, spleen and brain, C max and AUC 0-t of MBZ-OS were significantly increased than MBZ-1 tragacanth. Although no acute toxicity of MBZ-OS had been seen in this experiment, a long-term toxicity test is still necessary in the following study. In China, albendazole-emulsion is the dominant clinical formulation for patients with echinococcosis.